Dec 27, 2022·edited Dec 27, 2022Liked by Dr Ah Kahn Syed
Thank you arkmedic for making this all-important post.
The proof (that one commenter asked for) of what is happening is in epidemiology of Covid, excessive rates of cancer, and increased all-cause mortality.
I would like to retire early and live modestly. I cannot do that because I expect things to turn to much worse soon.
Very worried for the people I care about and everybody in general.
We were told three years ago that these “vaccines” would wreck your immune system in two to seven years. So sad that people couldn’t take a “wait and see” approach. That day is here.
Just finished reading this on Arkmedic’s Stack. I’m repeatedly reminded that my husband and I made the correct decision in not taking any of the poison jabs. We are both in our 60’s and in good health. When we contracted COVID it was managed easily with early IVM and HCQ with no lasting issues. We’re worried about our son, a medical “professional” who was fully on-board with the jabs from Day 1. He couldn’t wait to get his first and subsequent jabs! We were so disappointed that he wouldn’t even read any of the studies and information we sent to him. Even now, I believe he is still in full support of boosters...but can’t be sure since we cannot even mention COVID or jabs without a terrible row ensuing. So sad.
Contributors: Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology; Board on Chemical Sciences and Technology; Board on Life Sciences; Division on Earth and Life Studies; National Academies of Sciences, Engineering, and Medicine
Ralph Baric of UNC Chapel Hill was among the invited speakers.
Chapter 6 - ASSESSMENT OF CONCERNS RELATED TO BIOWEAPONS THAT ALTER THE HUMAN HOST
Modifying the Human Microbiome, 71
Modifying the Human Immune System, 74
Modifying the Human Genome, 77
pp. 74-77 - MODIFYING THE HUMAN IMMUNE SYSTEM
Human immunity is the bulwark for protection against infectious disease. Two basic systems respond to the vast array of threats in the natural environment. The first is the innate immune system, a collection of nonspecific protective mechanisms triggered by pathogen-associated molecular patterns, such as lipoteichoic acid from Gram-positive bacteria or unmethylated CpG sequences in viral DNA.
The second is the adaptive immune system, which generates highly specific antibody and T-cell responses tailored to individual diseases and disease variants.
Many natural pathogens manipulate the human immune system, both by suppressing the immune response (e.g., immunodeficiency viruses) and by upregulating certain responses (e.g., respiratory syncytial virus, which induces the immune system to favor a response involving Type 2 T helper cells [Th2] and subsequently increases the proclivity toward asthma [Lotz and Peebles, 2012]).
These examples suggest that it may be feasible to develop a bioweapon capable of manipulating or “engineering” the immune response.
Several potential forms for such a bioweapon were considered:
Engineering immunodeficiency.
Manipulating a target population to have decreased immunity could increase the impact of a biological attack. This goal could be pursued either by manipulating a pathogen to simultaneously reduce immunity and cause disease (Jackson et al., 2001) or by separately introducing an immune-suppressing agent and a bioweapon into a target population.
Agents used to cause immunodeficiency could be pathogens (e.g., the insidious spread of HIV [human immunodeficiency virus]) or chemicals (see NRC [1992] and IPCS [1996] for discussions of chemicals that contribute to immunotoxicity).
It is also possible that a disease agent could be tailored to the immune state of a population, either by engineering the agent to avoid extant adaptive or innate immune barriers or by actually taking advantage of those barriers (for further discussion see Chapter 7, Health-Associated Data and Bioinformatics).
Engineering hyperreactivity.
The flip side of engineering immune deficiencies would be to attempt to cause immune hyperreactivity. Both pathogens and chemicals have been demonstrated to create a cytokine storm, a dangerous state that results from a positive feedback loop in the immune response.
It may be possible to engineer an agent to purposefully trigger such a cascade. For example, some have suggested that the introduction of anthrax lethal toxin into a more benign disease vector could trigger a cytokine storm (Muehlbauer et al., 2007; Brojatsch et al., 2014; however, see Guichard et al., 2012 for a differing point of view).
Similarly, the fact that there are already widespread responses in the human population to a limited number of well-known allergens (ACAAI, 2017) may provide a means of engineering biological threats that would trigger life-threatening IgE-mediated immune responses. The development and testing of new immunotherapies could also provide a roadmap for potentially engineering threats; for example, actors could learn from clinical studies in which anti-CD28 antibodies caused life-threatening cytokine storms (Suntharalingam et al., 2006).
Engineering autoimmunity.
Natural autoimmune diseases cause significant disability and death. It may be possible to engineer a disease that causes the body to turn on itself. Mouse models for the stimulation of auto-immunity now exist.
For example, Experimental Autoimmune Encephalomyelitis, which mimics the symptoms of the human malady multiple sclerosis, has been induced in mice by immunization with antigens that cause an immune response (autoantigens; see Miller et al., 2007).
Normally, such self-immunization is prevented by the mechanisms that ensure exclusion of antibodies and T-cells that are self-reactive, but some pathogens may present antigens that are similar enough to the body’s own proteins that the original immune response spreads from the pathogen to the new human target.
Research into checkpoint inhibitors, compounds designed to unleash the human immune system to eradicate tumors, could also potentially inform efforts to purposely engineer autoimmunity. By overstimulating the immune system, checkpoint inhibitors have been shown to lead to autoimmunity, often in the form of colitis (June et al., 2017). In addition, particular compounds have been shown to lead to an autoimmune disease of the liver (Tanaka et al., 2017, 2018). One potential route of attack could be to introduce such compounds via the microbiome...
Usability of the Technology (Medium Concern)
It is difficult to predict precisely the impact of engineering on a system as complex as the immune system. We are only now beginning to more fully understand the mechanisms for how the immune system recognizes foreign antigens, and many immune mechanisms, such as how immune memory guides future responses, remain opaque. In addition, much of the research in this area is on animals, and the results do not necessarily map well to humans. Furthermore, while there has been an explosion of new research into the causes of autoimmunity, the onset of autoimmune disease remains idiosyncratic (Rosen and Casciola-Rosen, 2016), and it would likely be difficult to create immunomodulatory weapons capable of causing reliable effects in populations as genetically and immunologically diverse as the United States. In particular, while an immune deficiency virus pandemic has emerged naturally, engineering the spread of immune deficiency is currently difficult to imagine.
However, even undirected efforts in this area could be successful enough to warrant concern. In experiments in which mousepox was augmented with interleukin-4 (IL-4) (Jackson et al., 2001), earlier studies had already discerned that vaccinia virus altered with IL-4 increased virulence in mice (van den Broek et al., 2000), but it came as a surprise that the altered mousepox virus could also overcome vaccination against mousepox.
The failed clinical trial of anti-CD28 antibodies, in which patients suffered life-threatening cytokine storms after receiving doses 500 times lower than those shown safe in mouse models (Suntharalingam et al., 2006), offers another example. Although modeling studies indicated that the doses used would nearly saturate the T-cell population of a human (suggesting the potential for overactivation), the dramatic outcomes highlight the potential for inadvertent immune hyperreactivity as well as the dual-use potential of immunomodulation research. The concept of engineering a cytokine storm, especially in susceptible subpopulations, may become a concern when coupled with increasing knowledge of the immune system. For example, the growing knowledge of superantigens that hyperstimulate immunity could further increase the feasibility of such activities.
Our understanding of human immunity also represents an increasing, but unknown, area of concern. For example, with the advent of next-generation sequencing, the range of both B-cell and T-cell responses to vaccines can now be described in molecular detail. Similarly, the effectors of the pattern recognition receptors of the innate immune system are being defined to the point that engineering responses, both therapeutic and otherwise, are possible (Brubaker et al., 2015; Macho and Zipfel, 2015).
In addition, the continuing explosion of work in immunotherapy broadly could potentially create a roadmap for the development of immunomodulatory weapons. As understanding of this phenomenon improves and as the ability to engineer protein structures improves, the opportunities for creating synthetic simulacrum of antigens already known to be present in autoimmune diseases will increase. The opportunities to engineer autoimmunity are likely tempered by the diversity of potential auto- antigens that can be exploited, although this could also be viewed as a means of disease targeting as more and more personalized health data become available (see Chapter 7, Health-Associated Data and Bioinformatics).
On balance, given the challenges and both near- and longer-term opportunities, there is a medium level of concern with regard to usability of the technology for the variety of ways in which immunomodulation might be employed as a bioweapon....
Brilliant as always! Haunting, but brilliant. This is the worst fucking sci fi novel of all time, truly evil to force so many to take this poison with the threat of losing their jobs hanging over their heads and not being in the financial situation to have any real choice, I pray for a reckoning! Fuck off with your amnesty
Is this the same as VAIDS? Dr.Vanden Bossche has been warning us for a very long time. This was a thorough explanation of how the covid jabs overtime have destroyed the immune system. How is it possible so many took this poison without questioning its safety? I will never understand how educated adults were so easily conned.
As I read this I want to cry. My neighbor just developed ovarian cancer, and another one developed myeloma. I find it hard to read anymore, but I can’t ignore all this. All jabbed and boosted. Of course no one blames the vaccines. WAKE UP!!!
Regarding Paper 2. the Irrgang IgG4 paper. This is what I have been writing about from the patient perspective and how to get better again, or get less worse - passive exposure though. It felt like with each repeat flair-up - re-exposure - I got more sensitized, more reactive, more sick uicker, for longer. Autoimmune night sweats, swollen lymph nodes, fatigue, some congestion. I got more cautious about avoiding the public crowded or medical offices that are risky, or a busy restaurant. Treatment is vitally important and needs to be ongoing, and it would be nice if it became part of the conversation.
Pomegranate peel is a fusion inhibitor and something I use daily in addition to serrapeptase or nattokinase, and nicotine lozenges. Artemisinin, Artemisia extract, Wormwood tea, have all helped nip a flair-up in the bud. I use other nutrients too, but those four are significant - pom peel is an iron chelator, ACE2 agonist, COX2 inhibitor, in addition to being a fusion inhibitor and strong antimicrobial that benefits the microbiome. The fibrinolytics are important to reduce clot risk, especially at old wounds. Artemisinin is an iron chelator and antiparasitic and helps with the anemia of chronic inflammation that is part of "Long Illness"/ LongCovid. Nicotine lozenges are needed to prevent the cholinergic blocking effect of the S1 subunit on nAChRs. - That is likely the cause of the excess menstrual bleeding and miscarriage rate.
This continues to be so alarming and when I share these thoughts/finding etc. with "nay" sayers they comment things like, well YOU may have "your" side saying one thing but there are equally qualified Dr's etc. on "MY" side saying the opposite, saying they are safe and effective and continued to be recommended. From a friend who just got his 4th........ ( I am 17 months post 2nd and last EVER jab and am concerned DAILY, its bloody awful)
The horror! Luc Montagnier, Judy Mikovits, Bobby Kennedy, Vernon Coleman, Stephanie Seneff, Christiane Northrop, Dell Bigtree, Joseph Mercola, Sucharit Bhakdi, and Sherri Tenpenny warned us all several months before the jabs came out that they would wreck havoc with our health. They saved my life and all who would listen to me, but sadly many were brainwashed and would not listen.
Thank you for great work. I was unfamiliar with IgG subsets. Presumably the field of immunology is soon going to streamline its understanding of interplay between allergy and infection as it works its way through mRNA vaccine issues. Hopefully we discover the “long term non-progressor” scenario here as was found for AIDS
My doctor girlfriend takes allergy "vaccines", increasing doses of the allergen in order for the body to build up tolerance to them. I asked her why she expected this to work for allergies but the opposite to happen with constant boosters for the covid "vaccine". She took the huff.
If you, like me, had to know what PD-L1 stood for early on in this article, here is the answer:
PD-L1
A protein that acts as a kind of “brake” to keep the body’s immune responses under control. PD-L1 may be found on some normal cells and in higher-than-normal amounts on some types of cancer cells. When PD-L1 binds to another protein called PD-1 (a protein found on T cells), it keeps T cells from killing the PD-L1-containing cells, including the cancer cells. Anticancer drugs called immune checkpoint inhibitors bind to PD-L1 and block its binding to PD-1. This releases the “brakes” on the immune system and leaves T cells free to kill cancer cells.
Unless you possessed this knowledge, the remainder of the article did not allow the full impact intended...
Thank you arkmedic for making this all-important post.
The proof (that one commenter asked for) of what is happening is in epidemiology of Covid, excessive rates of cancer, and increased all-cause mortality.
I would like to retire early and live modestly. I cannot do that because I expect things to turn to much worse soon.
Very worried for the people I care about and everybody in general.
https://twitter.com/ichudov/status/1607730274745344000
Even the unvaxed people, swimming in a sea of chronic infections going around, will be affected.
We were told three years ago that these “vaccines” would wreck your immune system in two to seven years. So sad that people couldn’t take a “wait and see” approach. That day is here.
Just finished reading this on Arkmedic’s Stack. I’m repeatedly reminded that my husband and I made the correct decision in not taking any of the poison jabs. We are both in our 60’s and in good health. When we contracted COVID it was managed easily with early IVM and HCQ with no lasting issues. We’re worried about our son, a medical “professional” who was fully on-board with the jabs from Day 1. He couldn’t wait to get his first and subsequent jabs! We were so disappointed that he wouldn’t even read any of the studies and information we sent to him. Even now, I believe he is still in full support of boosters...but can’t be sure since we cannot even mention COVID or jabs without a terrible row ensuing. So sad.
To add: https://jessicar.substack.com/p/the-immunological-mechanism-of-action
Biodefense in the Age of Synthetic Biology, US National Academies of Sciences, Engineering, Medicine, June 19, 2018.
https://haseloff.plantsci.cam.ac.uk/resources/SynBio_reports/NAS_Biodefense2018.pdf
(https://bailiwicknews.substack.com/p/immunomodulation-and-fear-modulation)
Contributors: Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology; Board on Chemical Sciences and Technology; Board on Life Sciences; Division on Earth and Life Studies; National Academies of Sciences, Engineering, and Medicine
Ralph Baric of UNC Chapel Hill was among the invited speakers.
Chapter 6 - ASSESSMENT OF CONCERNS RELATED TO BIOWEAPONS THAT ALTER THE HUMAN HOST
Modifying the Human Microbiome, 71
Modifying the Human Immune System, 74
Modifying the Human Genome, 77
pp. 74-77 - MODIFYING THE HUMAN IMMUNE SYSTEM
Human immunity is the bulwark for protection against infectious disease. Two basic systems respond to the vast array of threats in the natural environment. The first is the innate immune system, a collection of nonspecific protective mechanisms triggered by pathogen-associated molecular patterns, such as lipoteichoic acid from Gram-positive bacteria or unmethylated CpG sequences in viral DNA.
The second is the adaptive immune system, which generates highly specific antibody and T-cell responses tailored to individual diseases and disease variants.
Many natural pathogens manipulate the human immune system, both by suppressing the immune response (e.g., immunodeficiency viruses) and by upregulating certain responses (e.g., respiratory syncytial virus, which induces the immune system to favor a response involving Type 2 T helper cells [Th2] and subsequently increases the proclivity toward asthma [Lotz and Peebles, 2012]).
These examples suggest that it may be feasible to develop a bioweapon capable of manipulating or “engineering” the immune response.
Several potential forms for such a bioweapon were considered:
Engineering immunodeficiency.
Manipulating a target population to have decreased immunity could increase the impact of a biological attack. This goal could be pursued either by manipulating a pathogen to simultaneously reduce immunity and cause disease (Jackson et al., 2001) or by separately introducing an immune-suppressing agent and a bioweapon into a target population.
Agents used to cause immunodeficiency could be pathogens (e.g., the insidious spread of HIV [human immunodeficiency virus]) or chemicals (see NRC [1992] and IPCS [1996] for discussions of chemicals that contribute to immunotoxicity).
It is also possible that a disease agent could be tailored to the immune state of a population, either by engineering the agent to avoid extant adaptive or innate immune barriers or by actually taking advantage of those barriers (for further discussion see Chapter 7, Health-Associated Data and Bioinformatics).
Engineering hyperreactivity.
The flip side of engineering immune deficiencies would be to attempt to cause immune hyperreactivity. Both pathogens and chemicals have been demonstrated to create a cytokine storm, a dangerous state that results from a positive feedback loop in the immune response.
It may be possible to engineer an agent to purposefully trigger such a cascade. For example, some have suggested that the introduction of anthrax lethal toxin into a more benign disease vector could trigger a cytokine storm (Muehlbauer et al., 2007; Brojatsch et al., 2014; however, see Guichard et al., 2012 for a differing point of view).
Similarly, the fact that there are already widespread responses in the human population to a limited number of well-known allergens (ACAAI, 2017) may provide a means of engineering biological threats that would trigger life-threatening IgE-mediated immune responses. The development and testing of new immunotherapies could also provide a roadmap for potentially engineering threats; for example, actors could learn from clinical studies in which anti-CD28 antibodies caused life-threatening cytokine storms (Suntharalingam et al., 2006).
Engineering autoimmunity.
Natural autoimmune diseases cause significant disability and death. It may be possible to engineer a disease that causes the body to turn on itself. Mouse models for the stimulation of auto-immunity now exist.
For example, Experimental Autoimmune Encephalomyelitis, which mimics the symptoms of the human malady multiple sclerosis, has been induced in mice by immunization with antigens that cause an immune response (autoantigens; see Miller et al., 2007).
Normally, such self-immunization is prevented by the mechanisms that ensure exclusion of antibodies and T-cells that are self-reactive, but some pathogens may present antigens that are similar enough to the body’s own proteins that the original immune response spreads from the pathogen to the new human target.
Research into checkpoint inhibitors, compounds designed to unleash the human immune system to eradicate tumors, could also potentially inform efforts to purposely engineer autoimmunity. By overstimulating the immune system, checkpoint inhibitors have been shown to lead to autoimmunity, often in the form of colitis (June et al., 2017). In addition, particular compounds have been shown to lead to an autoimmune disease of the liver (Tanaka et al., 2017, 2018). One potential route of attack could be to introduce such compounds via the microbiome...
Usability of the Technology (Medium Concern)
It is difficult to predict precisely the impact of engineering on a system as complex as the immune system. We are only now beginning to more fully understand the mechanisms for how the immune system recognizes foreign antigens, and many immune mechanisms, such as how immune memory guides future responses, remain opaque. In addition, much of the research in this area is on animals, and the results do not necessarily map well to humans. Furthermore, while there has been an explosion of new research into the causes of autoimmunity, the onset of autoimmune disease remains idiosyncratic (Rosen and Casciola-Rosen, 2016), and it would likely be difficult to create immunomodulatory weapons capable of causing reliable effects in populations as genetically and immunologically diverse as the United States. In particular, while an immune deficiency virus pandemic has emerged naturally, engineering the spread of immune deficiency is currently difficult to imagine.
However, even undirected efforts in this area could be successful enough to warrant concern. In experiments in which mousepox was augmented with interleukin-4 (IL-4) (Jackson et al., 2001), earlier studies had already discerned that vaccinia virus altered with IL-4 increased virulence in mice (van den Broek et al., 2000), but it came as a surprise that the altered mousepox virus could also overcome vaccination against mousepox.
The failed clinical trial of anti-CD28 antibodies, in which patients suffered life-threatening cytokine storms after receiving doses 500 times lower than those shown safe in mouse models (Suntharalingam et al., 2006), offers another example. Although modeling studies indicated that the doses used would nearly saturate the T-cell population of a human (suggesting the potential for overactivation), the dramatic outcomes highlight the potential for inadvertent immune hyperreactivity as well as the dual-use potential of immunomodulation research. The concept of engineering a cytokine storm, especially in susceptible subpopulations, may become a concern when coupled with increasing knowledge of the immune system. For example, the growing knowledge of superantigens that hyperstimulate immunity could further increase the feasibility of such activities.
Our understanding of human immunity also represents an increasing, but unknown, area of concern. For example, with the advent of next-generation sequencing, the range of both B-cell and T-cell responses to vaccines can now be described in molecular detail. Similarly, the effectors of the pattern recognition receptors of the innate immune system are being defined to the point that engineering responses, both therapeutic and otherwise, are possible (Brubaker et al., 2015; Macho and Zipfel, 2015).
In addition, the continuing explosion of work in immunotherapy broadly could potentially create a roadmap for the development of immunomodulatory weapons. As understanding of this phenomenon improves and as the ability to engineer protein structures improves, the opportunities for creating synthetic simulacrum of antigens already known to be present in autoimmune diseases will increase. The opportunities to engineer autoimmunity are likely tempered by the diversity of potential auto- antigens that can be exploited, although this could also be viewed as a means of disease targeting as more and more personalized health data become available (see Chapter 7, Health-Associated Data and Bioinformatics).
On balance, given the challenges and both near- and longer-term opportunities, there is a medium level of concern with regard to usability of the technology for the variety of ways in which immunomodulation might be employed as a bioweapon....
Brilliant as always! Haunting, but brilliant. This is the worst fucking sci fi novel of all time, truly evil to force so many to take this poison with the threat of losing their jobs hanging over their heads and not being in the financial situation to have any real choice, I pray for a reckoning! Fuck off with your amnesty
Is this the same as VAIDS? Dr.Vanden Bossche has been warning us for a very long time. This was a thorough explanation of how the covid jabs overtime have destroyed the immune system. How is it possible so many took this poison without questioning its safety? I will never understand how educated adults were so easily conned.
As I read this I want to cry. My neighbor just developed ovarian cancer, and another one developed myeloma. I find it hard to read anymore, but I can’t ignore all this. All jabbed and boosted. Of course no one blames the vaccines. WAKE UP!!!
Regarding Paper 2. the Irrgang IgG4 paper. This is what I have been writing about from the patient perspective and how to get better again, or get less worse - passive exposure though. It felt like with each repeat flair-up - re-exposure - I got more sensitized, more reactive, more sick uicker, for longer. Autoimmune night sweats, swollen lymph nodes, fatigue, some congestion. I got more cautious about avoiding the public crowded or medical offices that are risky, or a busy restaurant. Treatment is vitally important and needs to be ongoing, and it would be nice if it became part of the conversation.
Pomegranate peel is a fusion inhibitor and something I use daily in addition to serrapeptase or nattokinase, and nicotine lozenges. Artemisinin, Artemisia extract, Wormwood tea, have all helped nip a flair-up in the bud. I use other nutrients too, but those four are significant - pom peel is an iron chelator, ACE2 agonist, COX2 inhibitor, in addition to being a fusion inhibitor and strong antimicrobial that benefits the microbiome. The fibrinolytics are important to reduce clot risk, especially at old wounds. Artemisinin is an iron chelator and antiparasitic and helps with the anemia of chronic inflammation that is part of "Long Illness"/ LongCovid. Nicotine lozenges are needed to prevent the cholinergic blocking effect of the S1 subunit on nAChRs. - That is likely the cause of the excess menstrual bleeding and miscarriage rate.
My Protocol Collation and Therapy Goals. 12/15/2021 - work in progress draft, useful but not beautiful. https://docs.google.com/document/d/1RmdgbxBUuJa9nFUmCfSoZdnEB8EPc181WOvhGakAKTU/edit?usp=sharing See Chapter Six for the autoimmune issue caused by the jabs; subsection: ADE & Neutralizing Vs Non-Neutralizing Antibodies - Leaky Vak and autoimmune risks. *This is not new news.
Passive exposure is a big deal, just not as bad as getting the jabs directly.
This continues to be so alarming and when I share these thoughts/finding etc. with "nay" sayers they comment things like, well YOU may have "your" side saying one thing but there are equally qualified Dr's etc. on "MY" side saying the opposite, saying they are safe and effective and continued to be recommended. From a friend who just got his 4th........ ( I am 17 months post 2nd and last EVER jab and am concerned DAILY, its bloody awful)
The horror! Luc Montagnier, Judy Mikovits, Bobby Kennedy, Vernon Coleman, Stephanie Seneff, Christiane Northrop, Dell Bigtree, Joseph Mercola, Sucharit Bhakdi, and Sherri Tenpenny warned us all several months before the jabs came out that they would wreck havoc with our health. They saved my life and all who would listen to me, but sadly many were brainwashed and would not listen.
Thank you for great work. I was unfamiliar with IgG subsets. Presumably the field of immunology is soon going to streamline its understanding of interplay between allergy and infection as it works its way through mRNA vaccine issues. Hopefully we discover the “long term non-progressor” scenario here as was found for AIDS
My doctor girlfriend takes allergy "vaccines", increasing doses of the allergen in order for the body to build up tolerance to them. I asked her why she expected this to work for allergies but the opposite to happen with constant boosters for the covid "vaccine". She took the huff.
Nice work. Substack told me this was an 8-minute read. Ha, not for me!
If you, like me, had to know what PD-L1 stood for early on in this article, here is the answer:
PD-L1
A protein that acts as a kind of “brake” to keep the body’s immune responses under control. PD-L1 may be found on some normal cells and in higher-than-normal amounts on some types of cancer cells. When PD-L1 binds to another protein called PD-1 (a protein found on T cells), it keeps T cells from killing the PD-L1-containing cells, including the cancer cells. Anticancer drugs called immune checkpoint inhibitors bind to PD-L1 and block its binding to PD-1. This releases the “brakes” on the immune system and leaves T cells free to kill cancer cells.
Unless you possessed this knowledge, the remainder of the article did not allow the full impact intended...
"Thing was, he already had lymphoma. It was quite well controlled in fact (as some lymphomas can be with the right treatment)."
I think his left-side lymphoma was caused by left-arm primary series. Right-arm booster caused boosted right-side lymphoma on steroids.
PEG is a carcinogen. Add immunosuppression. Double whammy.
Please see my my comment posted in the Annals of Internal Medicine:
https://www.acpjournals.org/doi/full/10.7326/M21-0111
"PEG is contaminated with 1,4-dioxane, a carcinogen.
https://www.fda.gov/cosmetics/potential-contaminants-cosmetics/14-dioxane-cosmetics-manufacturing-byproduct"